Multivitamins (Z-Gain)

Z-Gain – MultiVitamin Tablets

Z-Gain – MultiVitamin (Mecobalamin 1500 mcg, Benfotiamine 200 mg, Folic Acid 1.5 mg, Chromium Polynicotinate 200 mcg, Myo-inositol 100 mg, Pyridoxine Hydrochloride 3 mg Tablets)

The combination is generally prescribed for memory enhancement, neurological and cognitive disorder, Parkinsonism and Alzheimer disorder.

Overview

  • Methylcobalamin or Mecobalamin stimulates cell lecithin synthesis, repairs damaged myelin and thereby improves nerve conduction velocity.1
  • It is a safe and potentially efficacious therapy for patients with peripheral neuropathy and chronic axonal degeneration.2
  • Methylcobalamine promotes axonal growth in peripheral nerve injury.2
  • It exerts neuronal protection by promoting regeneration of injured nerves and antagonizing glutamate-induced neurotoxicity.3
  • Methylcobalamin alleviated pain behaviors in diabetic neuropathy, low back pain and neuralgia.3
  • It improves nerve conduction, promotes the regeneration of injured nerves, and inhibites ectopic spontaneous discharges of injured primary sensory neurons.3
  • It has potential analgesic effects on neuropathic pain in experimental and clinical studies.3
  • Methylcobalamin recovers the neuromuscular functions in peripheral hyperalgesia and allodynia.3
  • Methylcobalamin treatment is helpful in relieving pain and improving the quality of life1

Ref:

1. BMC Cancer (2017) 17:40.

2. Intern Med. 2014;53(17):1927-31.

3. Neural Plasticity 2013, 424651. http://dx.doi.org/10.1155/2013/424651

  • Methylcobalamin was more effective than the placebo in relieving non- specific low backpain (NSLBP) and its related disability.1
  • Patients with NSLBP required significantly less analgesics, and had improvements in their disability scores.1
  • Therapeutic action of methylcobalamin is exhibited by analgesic and analgesia-potentiating/enhancing properties, as well as its neurosynthesis/neuroprotective properties.1
Methylcobalamin vs Placebo

Ref:

1. Singapore Med J 2011; 52(12) : 868 -73